// MongoClient.connect(uri, {  ignoreUndefined: true })

db.collection('Test').findOneAndUpdate(
    {
        test: 'test'
    },
    {
        $set: {
            undefined_1: undefined,
            null_1: null,
        },
        $setOnInsert: {
            undefined_2: undefined,
            null_2: null,
        }
    },
    {
        upsert: true
    }
)

{
  test: 'test',
  null_1: null,
  null_2: null
}

{
  test: 'test',
  undefined_1: null,
  null_1: null,
  undefined_2: null,
  null_2: null
}